”As disabled people engaged in disability community, activism, and scholarship, [their] collective experiences and histories have taught that [they] are effective agents of world building and dismantling toward more socially just relations. The grounds for social justice and world remaking, however, are frictioned; technologies, architectures, and infrastructures are often designed and implemented without committing to disability as a difference that matters. This manifesto calls attention to the powerful, messy, non-innocent, contradictory, and nevertheless crucial work of what [is named] as 'crip technoscience,' practices of critique, alteration, and reinvention of [the] material-discursive world. Disabled people are experts and designers of everyday life. But [they] also harness technoscience for political action, refusing to comply with demands to cure, fix, or eliminate disability. Attentive to the intersectional workings of power and privilege, [they] agitate against independence and productivity as requirements for existence. Instead, [they] center technoscientific activism and critical design practices that foster disability justice.”